Saline Vehicle Increase the Ability of Drug Patch Test in Cutaneous Adverse Drug reactions
Phase 1
Completed
- Conditions
- To evaluate the efficacy of drug patch test using 0.9% saline vehicle and comparison with standard vehicles in CADRs.Drug patch test
- Registration Number
- TCTR20200805005
- Lead Sponsor
- self-funded
- Brief Summary
sing saline as a vehicle can increase the positive reaction of drug patch test, particularly in lichenoid drug eruption. The positive drug patch test results may depend on the clinical presentation, drug categories and patch test vehicles. We recommend to use saline as another standard vehicle in drug patch test.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
patients who were diagnosed with delayed type hypersensitivity CADRs. including DRESS, MP rash, FDE, lichenoid drug eruption, exfoliative dermatitis, Eczematous drug eruption, SJS/TEN and AGEPby dermatologists from outpatient and inpatient units of a tertiary referral medical center, Phramongkutklao Hospital
Exclusion Criteria
We excluded patients with type 1 hypersensitivity CADRs and patients who currently on immunosuppressive drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method positive 48, 96 hours Drug patch test
- Secondary Outcome Measures
Name Time Method safety reading 48, 96 hours patch test