Respiratory Complications of Operated Esophageal Atresia in Children

Completed

• Conditions: Esophageal Atresia

• Registration Number: NCT05527873
• Lead Sponsor: University Hospital, Strasbourg, France

Brief Summary

The respiratory complications of esophageal atresia have already been identified.

They are mainly related to tracheomalacia linked to the esophageal malformation, and are aggravated by frequently associated gastroesophageal reflux.

In this context, symptoms of asthma (or bronchial hyperreactivity) occur more frequently than in the general population and persist into adulthood. Their pathogenesis is still poorly understood and is the subject of much discussion.

The therapeutic management of these respiratory complications, poorly codified, remains very heterogeneous from one center to another. In France, the summary of knowledge is updated by the Reference Center for chronic and malformative diseases of the esophagus.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-03-16
• Study First Submitted: 2022-09-01
• Study First Submitted QC: 2022-09-01
• Study First Posted: 2022-09-06
• Primary Completion: 2022-10-16
• Study Completion: 2022-12-16
• Status Verified: 2023-11
• Last Update Submitted: 2023-11-07
• Last Update Posted: 2023-11-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 67

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Retrospective study of respiratory complications of esophageal atresia in children	Files analysed retrospectively from January 01, 2010 to December 31, 2020 will be examined

Trial Locations

Locations (1)

Centre de Ressources et de Compétences de la Mucoviscidose (CRCM) - CHU de Strasbourg - France; 🇫🇷 Strasbourg, France