Characterization and Analysis of Evoked Cortical Responses in Participants With Medication-intractable Epilepsy

Not Applicable

Recruiting

• Conditions: Intractable Epilepsy

• Registration Number: NCT07014592
• Lead Sponsor: University of Michigan

Brief Summary

The goal of this project is to study how the brain reacts to a small electrical signal. Researchers will be using a novel combination of recording electrodes. The researchers will measure the brain response from these electrodes.

Detailed Description

Not available

Study Timeline

• Study Start: 2025-05-05
• Study First Submitted: 2025-05-24
• Status Verified: 2025-06
• Study First Submitted QC: 2025-06-09
• Last Update Submitted: 2025-06-09
• Study First Posted: 2025-06-11
• Last Update Posted: 2025-06-11
• Primary Completion: 2026-05
• Study Completion: 2026-05

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 5

Inclusion Criteria

• Patients with medication intractable epilepsy who are recommended to undergo brain surgery to remove a "seizure" focus
• Can provide informed consent for the study and willing to participate

Exclusion Criteria

• Presence of a permanent electronic implant
• Any chronic medical conditions that prevent safe placement of electrodes

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Characterization of time-frequency data	During a 20 minute research phase of a clinically indicated surgery	From recording electrodes
Characterization of local field responses (LFPs)	During a 20 minute research phase of a clinically indicated surgery	From recording electrodes

Trial Locations

Locations (1)

University of Michigan; 🇺🇸 Ann Arbor, Michigan, United States