NCT00219804已完成3 期
A Randomized, Double-Blind, Placebo-Controlled Study of Tetrabenazine for the Treatment of Huntington's Chorea
Prestwick Pharmaceuticals0 个研究点开始时间: 2005年9月22日最近更新:
适应症
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
研究概览
简要总结
The primary objective of this study was to establish the absolute reduction of chorea in participants with Huntington's disease(HD) treated with tetrabenazine or placebo
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18 years of age or older
- •suffer from manifest HD as confirmed by genetic testing
- •Meet chorea and total functional capacity scores on Unified Huntington's Disease Rating Scale
- •Meet criteria on Hamilton Depression Rating Scale, Unified Parkinson's Disease Rating Scale dysphagia and dysarthria scale
- •Independently ambulatory
排除标准
- •previous treatment with tetrabenazine
- •unstable or serious medical or psychiatric illness
- •concomitant use identified drugs
- •untreated depression
- •lack of caregiver
研究者
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