An open-label, randomized, parallel arm trial to investigate the pharmacokinetics and pharmacodynamics of NOMAC-E2 and ENG-E2 containing vaginal ring formulations in women of childbearing potential
Completed
- Conditions
- Anticonceptiecontraceptive
- Registration Number
- NL-OMON35882
- Lead Sponsor
- Schering-Plough
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Healthy females, 18-45 years of age, BMI 18-30 kg/m2
Exclusion Criteria
Clinical significant abnormalities at screening
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The objective of this trial is to study how E2, NOMAC and ENG (the test<br /><br>medication) are absorbed, distributed and broken-down by the body during usage<br /><br>of a vaginal ring that releases either NOMAC and E2 or ENG and E2 and to<br /><br>investigate the effect of this vaginal ring on the functioning of the ovaries.</p><br>
- Secondary Outcome Measures
Name Time Method <p>-</p><br>