A Randomized Controlled Trial Comparing Selective Laser Trabeculoplasty and Timolol for Treatment of Glaucoma in Tanzania
- Conditions
- Eye DiseasesGlaucoma
- Registration Number
- PACTR201508001235339
- Lead Sponsor
- ondon School of Hygiene & Tropical Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Other
- Sex
- All
- Target Recruitment
- 360
IOP above 21mmHg in the study eye
Open chamber angle with sufficient visualisation of angle structures (Shaffer II or more) on Gonioscopy
Clear media (cornea, anterior chamber) to visualise the chamber angle
Glaucomatous optic disc changes (structural changes due to glaucoma) with or without glaucomatous visual field defects (functional changes due to glaucoma) or high risk chronic open-angle glaucoma suspect.
Ability to provide informed consent
Willingness to return for regular follow-up visits
Pseudophakic patients will be enrolled if the chamber angle is open and the anterior segment shows no signs of inflammation.
No perception of light
History of previous glaucoma surgery including other laser treatment
History of previous uveitis
Neovascular glaucoma
Physical inability to administer topical treatment
Age below 18 years.
Pregnant women
History of asthma, bradycardia, previous heart failure, hypersensitivity to beta-blockers or systemic use of beta-blockers.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Success defined as intraocular pressure below or equal to target pressure
- Secondary Outcome Measures
Name Time Method Success rates with fixed thresholds and mean intraocular pressure;Visual acuity and visual field;Complication rates;Quality of life and other patient reported outcomes;Cost analysis;Qualitative analysis;Structural changes of the optic disc, cornea or other affected structures