Outcomes of Surgery of Aortic Valve

• Conditions: Aortic Valve Disease
• Interventions: Procedure: Aortic valve replacement

• Registration Number: NCT04277572
• Lead Sponsor: Assiut University

Brief Summary

Overall Goal: To study the outcomes of patients undergoing aortic valve surgeries, different approaches such as standard aortic valve replacement, aortic valve repair, novel techniques as Ozaki's procedure and their subsequent results and complications.

* Objective 1: Identify predictors of complications following different types of aortic valve surgery accordingly.

* Objective 2: Determine the value of each type in terms of advantages and disadvantages.

* Objective3: Assess outcomes such as postoperative life expectancy, hospital stay, prognosis and quality of life.

Detailed Description

Not available

Study Timeline

• Status Verified: 2020-02
• Study First Submitted: 2020-02-17
• Study First Submitted QC: 2020-02-19
• Last Update Submitted: 2020-02-19
• Study First Posted: 2020-02-20
• Last Update Posted: 2020-02-20
• Study Start: 2020-03-01
• Primary Completion: 2022-02-28
• Study Completion: 2022-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Patients with severe symptomatic aortic valve lesion.

2. Asymptomatic aortic insufficiency patients with left ventricular dysfunction or significant left ventricular dilatation (LV end diastolic diameter>70 mm or LV end systolic diameter>50 mm.

3. Patients with aortic regurgitation caused by:

   • a dilated aortic annulus
   • conjoined cusp prolapse in bicuspid aortic valves (BAV)
   • single cusp prolapse in tricuspid aortic valves
   • aortic valve cusp perforation from endocarditis

Exclusion Criteria

• Patients with previous aortic root or valve surgery.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Aortic valve replacement	Aortic valve replacement	using different ways of aortic valve replacement either by prosthetic valves or by ozaki technique

Primary Outcome Measures

Name	Time	Method
Outcomes of different techniques of aortic valve surgery in the indicated patients for each type of surgery such as :	Up to one week	Number of days of postoperative hospital stay.