The Risk of Adverse Pregnancy Outcomes for Long-term Exposure to Air Pollution in Pregnant Patients With Pulmonary Hypertension
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,200
- 试验地点
- 1
- 主要终点
- 1.main maternal outcome
研究概览
简要总结
With economic development and rapid urbanization, air pollution has become an increasingly severe public health concern. The risk of adverse pregnancy outcomes is significantly elevated for pregnant women complicated by pulmonary hypertension. However, no studies to date have specifically examined the impact of environmental factors on pulmonary hypertension in pregnant women, nor their subsequent birth outcomes. Therefore, investigating the correlation between them holds substantial clinical and public health significance.
详细描述
The purpose of the research is preliminary found that the correlation between air pollution and maternal outcomes in pregnant women with pulmonary arterial hypertension and provide useful information for managment of pregnant women in special ambient conditions.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Pregnant women with pulmonary hypertension who attended major medical centers included in this study from January 2013 to December
- •Complete medical records available; ② Pulmonary artery systolic pressure ≥ 35 mmHg by echocardiography or a confirmed diagnosis of pulmonary hypertension by right heart catheterization; ③ Residential address information available at the city (district, county) level or higher.
排除标准
- •① Unclear diagnosis and completely missing address information;
- •Incomplete medical records; ③ Lost to follow-up during pregnancy or within six weeks postpartum.
结局指标
主要结局
1.main maternal outcome
时间窗: diagnosis of pregnancy to six months postpartum
including maternal death and heart failure
次要结局
- Secondary maternal outcome events(From delivery to 42 days postpartum)
研究者
Wei Huang
Professor
First Affiliated Hospital of Chongqing Medical University