An open label single arm clinical study on combined effect of Prasarini Taila Matra Basti and Parasarini Capsule in Janusandhigatavata (Osteo-Arthritis of Knee)

Sandhigata vata is one among Vatavyadhis. Janu sandhigata vata is presented with symptoms like Vatapoornadruti Sparsha, Shotha, Shoola on Prasarana and Akunchana at Janu sandhi.

Janu sandhigata vata has the similar features of Osteoarthritis, which is the most common type of arthritis occurring in weight bearing joints like hip and knee. Main presenting symptoms are pain and functional restriction. When it occurs in knee, pain is localized to anterior or medial aspect of knee which worsens on going up and down stairs. The prevalence of osteoarthritis rises progressively with age and it has been estimated that 45% of all people develop osteoarthritis during their life. With 6% incidence of age >30 years and 12% incidence >60 years.

Charaka has mentioned Basti as Ardha chikitsa. Matra basti is Balya, Brumhana and Vatahara. Prasarini taila is mentioned in Bhavaparakashpossess Vatahara, Balya and Rasayana properties which helps in relieving the symptoms of the Sandhigata vata.

Prasarini mentioned in Ayurvedic Pharmacopeia of Indiahas Tikta Rasa, Katu vipak, Ushna veerya, Guru and Sara properties. Prasarini pacifies Vata because of its Ushna veerya, Guru and Sara properties. Prasarini capsule will be administered orally.

Hence, this study is taken to evaluate combined effect of Prasarini capsule and Prasarini taila in janusandhigata vata.