Prevalence and Incidence of Multiple Revisions Following Knee Arthroplasty in Denmark 1998-2021: A Nationwide Population-based Study

Completed

• Conditions: Knee Replacement; Knee Replacement Revision
• Interventions: Procedure: Revision

• Registration Number: NCT06064318
• Lead Sponsor: Rigshospitalet, Denmark

Brief Summary

The purpose of this study is to investigate the incidence and prevalence rates of multiply revised knee arthroplasty patients in Denmark from 1998-2021.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-02-01
• Primary Completion: 2023-09-02
• Study First Submitted: 2023-09-26
• Study First Submitted QC: 2023-09-26
• Study First Posted: 2023-10-03
• Status Verified: 2024-04
• Study Completion: 2024-04-01
• Last Update Submitted: 2024-04-09
• Last Update Posted: 2024-04-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 161384

Inclusion Criteria

• Danish Resident
• between 18-99 years of age
• must have had primary knee arthroplasty procedure performed in Denmark between 1998-2021

Exclusion Criteria

• Missing key variables (patient ID, date of surgery, procedure-code, laterality of procedure)
• Duplicates
• Non-relevant procedures

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Revision cohort	Revision	All patients with a revision knee arthroplasty performed in Denmark between Jan 1st 1998 and 31st December 2021

Primary Outcome Measures

Name	Time	Method
Prevalence of all n-grade revisions	23 years	standardized prevalence of all n-grade revisions
Prevalence of major n-grade revisions	23 years	standardized prevalence of major n-grade revisions
Incidence of major n-grade revisions	23 years	standardized incidence of major n-grade revisions
Incidence of all n-grade revisions	23 years	standardized incidence of all n-grade revisions

Secondary Outcome Measures

Name	Time	Method
Prevalence of major and all n-grade revisions stratified by sex and age	23 years	Calculation of prevalence for major and for all n-grade revisions stratified by sex and by age (groups, sex: male/female, age: 18-49/50-69/70-99)
Prevalence of major and all n-grade revisions for patients with their total sum of revisions	23 Years	Calculation of standardized prevalence for patients receiving major or all type of n-grade revision, where the ordering of revisions are not knee specific but patient-specific
Incidence of major and all n-grade revisions stratified by sex and age	23 years	Calculation of incidence for major and for all n-grade revisions stratified by sex and by age (groups, sex: male/female, age: 18-49/50-69/70-99)

Trial Locations

Locations (1)

Rigshospitalet; 🇩🇰 Copenhagen, Denmark