Effective dose of aspirin for prevention of a type of hypertension in pregnancy
Not Applicable
Completed
- Conditions
- Health Condition 1: O100- Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
- Registration Number
- CTRI/2021/07/034646
- Lead Sponsor
- Balram pandit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
�Previous history of preeclampsia
�nulliparity
�short( <12months) or long (72months) inter pregnancy interval
�h/o ART
�family h/o chronic hypertension.
�Obesity (BMI >29.9)
�comorbidities like SLE, chronic hypertension, APS, kidney disease, DM
Exclusion Criteria
1.allergic to aspirin and aspirin is contra indicated for medical reasons
2.refusal for consent
3.significant fetal malformations or presence of aneuploidy
4.low platelet count
5. patient on anticoagulation
6. patient already on aspirin
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1 Incidence of preterm preeclampsia in both groups. <br/ ><br>2 Complications of preeclampsia like HELLP, Eclampsia, acute kidney injury and postpartum eclampsia <br/ ><br>Timepoint: 1 year <br/ ><br>
- Secondary Outcome Measures
Name Time Method .Incidence of antepartum and postpartum hemorrhage <br/ ><br> Gestation at delivery, mode of delivery. <br/ ><br> Need for blood transfusion and hospitalization for maternal or fetal indication. <br/ ><br> Development of IUGR, IUFD, fetal distress, neonatal death. <br/ ><br> Hemorrhagic disease of new born, respiratory distress in the newborn <br/ ><br> APGAR score, duration of NICU stay of the baby <br/ ><br>Timepoint: 1 YEAR