Ultrasound Study Through Uterine Texturization to Predict Pregnancy After Blastocyst Transfer in Patients Undergoing Hormone Replacement Therapy (HRT) Cycles With Donor Oocytes
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 试验地点
- 1
- 主要终点
- Chemical pregnancy rate
研究概览
简要总结
This study is focused on analysing the application of ultrasound scanning techniques as new biomarkers in reproductive medicine. Those biomarkers are based on the analysis of ultrasound texture in different areas of uterine tissue, using 2D/3D ultrasound scanning. Investigators will use the algorithm Text® to analyse the ultrasound texture of the endometrium and myometrium. The aim of the project is to study if it is possible to obtain measurable, objective and reproducible data in healthy volunteers which can be used to predict pregnancy and determine the best moment to perform embryo transfer in assisted reproductive technology (ART) cycles
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 49 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Body mass index (BMI) between 18 and 30 kg/m2
- •Not taking the contraceptive pill in a previous cycle
- •Non-pregnant: beta human chorionic gonadotropin (HCG) test with negative result at the beginning of the study)
- •No previous history of inflammatory diseases, circulatory diseases, abdomen or pelvic diseases
- •Physical gynecological exploration without pathological findings
- •Gynecological ultrasound study of the uterus with a normal result
排除标准
- •Ultrasound studies with technical defects in image acquisition
- •Simultaneous participation in other studies
- •Previous participation in other study which can affect the results of the present study
结局指标
主要结局
Chemical pregnancy rate
时间窗: Around 14 days after embryo transfer
Positive result in beta HCG test indicating pregnancy
Clinical miscarriage rate
时间窗: Up to 20 weeks after embryo transfer
Interruption of pregnancy after confirming clinical pregnancy using ultrasound scanning
beta HCG level
时间窗: Around 14 days after embryo transfer
Level of beta HCG in the test performed to detect pregnancy
Clinical pregnancy rate
时间窗: Around 5-6 weeks after embryo transfer
Detection of gestational sac through ultrasound scanning indicating clinical pregnancy
Biochemical miscarriage rate
时间窗: Up to one month after embryo transfer
Interruption of pregnancy after a positive result in the beta HCG test
次要结局
未报告次要终点