TCTR20201228004尚未招募未知
Multimodal analgesia study of nefopam combined with ketorolac, paracetamol and gabapentin compare to morphine in postoperative unilateral total knee arthroplasty
erdsin hospital0 个研究点目标入组 100 人开始时间: 2020年12月28日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 0 N/A (No limit) 至 0 N/A (No limit)（—）
- 性别
- All
入选标准
- •1.Postoperative unilateral total knee arthroplasty patients.
- •2.Patients whose medial collateral ligament were not released
- •3.Underwent spinal block without morphine injection to subarachnoid space
排除标准
- •1.Cannot give information about VAS
- •2.History of knee surgery same side of total knee arthroplasty
- •3.BMI equal or more than 40 kg/square meters
- •4.Underlying disease that are contraindicated to nefopam, ketorolac, paracetamol, gabapentin, morphine : chronic liver disease, cardiac or chronic renal failure(GFR < 90 ml/min/1.73m2), psychiatric disorder, alcohol abuse, glaucoma, peptic ulcer, inflammatory bowel disease, established, ischemic heart disease, suicidal idea
- •5.History of drug allergy to sulfonamides group
- •6.Allergy to aspirin, NSAIDs, selective COX-2 inhibitors
研究者
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