Moxibustion for Mild and Moderate Ulcerative Colitis

Not Applicable

Completed

• Conditions: Ulcerative Colitis

• Registration Number: NCT02084186
• Lead Sponsor: Shanghai Institute of Acupuncture, Moxibustion and Meridian

Brief Summary

The purpose of this study is to determine whether moxibustion is effective to mild and moderate ulcerative colitis and the effect of moxibustion on metabolism.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-03
• Study First Submitted: 2014-03-09
• Study First Submitted QC: 2014-03-09
• Study First Posted: 2014-03-11
• Status Verified: 2015-12
• Primary Completion: 2015-12
• Study Completion: 2015-12
• Last Update Submitted: 2016-10-10
• Last Update Posted: 2016-10-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Meet the diagnosis of UC
• Mayo ≤10
• Patients should have never received any pharmacological therapy or if they are receiving aminosalicylates and/or prednisolone (the dosage has been taken at least 4 weeks, and should be kept the same as before throughout the trial)
• Patients should have never received antibiotic, biologicals, probiotics, acetaminophen, acetamide and contraceptive.
• A written informed consent

Exclusion Criteria

• Patients with cardiac, encephalic, hepatic, nephric, hematopoietic system, psychotic or any other serious diseases
• Pregnancy or lactation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
disease activity index (DAI)	3 months	Using Mayo subscore

Secondary Outcome Measures

Name	Time	Method
symptom score	3 months
metabolic profile of intestinal mucosa, urine, plasma and serum	3 months
Inflammatory Bowel Disease Questionnaire (IBDQ)	3 months
histomorphology observation of intestinal mucosa	3 months	Using the Geboes histology score

Trial Locations

Locations (1)

Shanghai Institute of Acupuncture-Moxibustion and Meridian; 🇨🇳 Shanghai, China