Screening for Chronic Kidney Disease among Older People across Europe (SCOPE)

Completed

• Conditions: Chronic Kidney Disease; End Stage Renal Disease; 10029149

• Registration Number: NL-OMON46292
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 350

Inclusion Criteria

All patients and their spouses aged 75 and over, attending the outpatient services at participating institutions.

Exclusion Criteria

Only patients with ESRD or dialysis, history of solid organ or bone marrow transplantation, active malignancy within 24 months prior to screening or metastatic cancer, life expectancy less than 6 months, severe cognitive impairment (MMSE<10), any medical or other reason (e.g. known or suspected inability of the subject to comply with the protocol procedure) that investigator opinion that the subject is unsuitable for the study, and patients unwilling to provide consent and those who cannot be followed-up will be excluded from the study.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary study endpoints will be the rate of eGFR decline and the incidence<br /><br>of ESRD.<br /><br>- Creatinine-based eGFR will be calculated using the Berlin Initiative Study 1<br /><br>(BIS1) equation, which is the only method specifically developed in a<br /><br>population older than 70 years<br /><br>- ESRD will be defined as GFR <15 mL/min/1.73 m2 or dialysis.</p><br>