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Clinical Trials/CTRI/2025/12/098472
CTRI/2025/12/098472Not yet recruitingNot Applicable

Comparison of Spirometry-Guided Tidal Volume and Conventional Ventilation on Postoperative Respiratory Complications in Adolescents Undergoing General Anaesthesia: A Randomized Controlled Trail

All India Institute of Medical Sciences, Bibinagar1 site in 1 country102 target enrollmentStarted: December 13, 2025Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Enrollment
102
Locations
1

Study Overview

Brief Summary

This randomized controlled study investigates whether using spirometry-guided tidal volume can offer superior perioperative lung protection compared with conventional weight-based tidal volume ventilation in adolescents undergoing general anaesthesia. By individualizing ventilation based on each patient’s spirometric capacity, the study aims to reduce intraoperative atelectasis, improve lung aeration as assessed by Lung Ultrasound Score, and ultimately lower the incidence of postoperative respiratory complications, potentially establishing a more physiologically precise approach to adolescent perioperative ventilation.

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
None

Eligibility Criteria

Ages
10.00 Year(s) to 19.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • ASA 1 and 2 patients coming for GA lasting at least for 1 hour.

Exclusion Criteria

  • patients undergoing emergency surgeries, ASA grade more than 3, CDC growth charts BMI less than 5th percentile and more than 85th percentile, patients with any history of previous lung surgery, persistent hemodynamic instability, history of chronic/acute disease, patient with any neuromuscular disease.

Investigators

Sponsor
All India Institute of Medical Sciences, Bibinagar
Sponsor Class
Government medical college
Responsible Party
Principal Investigator
Principal Investigator

Devalla Deva Datta

AIIMS BIBINAGAR

Study Sites (1)

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