Adaptive Cognitive Training in Healthy Older Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 99
- 试验地点
- 2
- 主要终点
- Change in neural activity
研究概览
简要总结
Cognitive training has emerged as a promising method to maintain, enhance, and rehabilitate cognitive function in older adults and individuals with dementia. In recent years, such training has become particularly appealing in the clinical context, with many paradigms aimed specifically at adults experiencing various stages of cognitive decline due to Mild Cognitive Impairment, Alzheimer's disease, and vascular dementias. However, basic questions remain. For example, uncertainty persists regarding factors that influence observed improvements as well as the conditions that would maximize transfer and sustainability of training effects. The objective of this study is to evaluate factors that may maximize the benefits of computerized cognitive training in older adults.
详细描述
The study involves 25 sessions of an adaptive cognitive training program, completed over 5 weeks. Pre and post training assessments will evaluate any near and far transfer effects of training.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •English as the maternal or primary spoken language.
- •Good self-reported health (i.e., no cerebro-, or cardio-vascular disease or neurological disease).
- •Normal or corrected-to-normal vision and hearing.
排除标准
- •Poor hearing or vision
- •Inadequate understanding of the English language
研究组 & 干预措施
Computerized cognitive training
Series of gamified tasks.
干预措施: Computerized cognitive training (Other)
Computerized game training
Series of gamified tasks.
干预措施: Computerized games (Other)
结局指标
主要结局
Change in neural activity
时间窗: Baseline, week 5
We will measure resting state as well as task-related EEG responses to determine the effects of cognitive training at the neural level.
Change in ratings on cognitive training survey
时间窗: Baseline, week 5
This survey aims to assess participant perceptions on cognitive training, and includes a series of related questions, rated on a scale of 1-7.
Change in performance on neuropsychological tests
时间窗: Baseline, week 5
Using a set of standard neuropsychological evaluations, we will measure changes in attention, memory, and executive function following cognitive training.
次要结局
- Change in ratings of psychological wellbeing(Baseline, week 5)