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Clinical Trials/NCT02515318
NCT02515318
Unknown
Not Applicable

Effects of a Physiotherapy Program in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Universidad de Granada2 sites in 1 country60 target enrollmentSeptember 2015

Overview

Phase
Not Applicable
Intervention
Physiotherapy program
Conditions
COPD
Sponsor
Universidad de Granada
Enrollment
60
Locations
2
Primary Endpoint
Muscle strength
Last Updated
7 years ago

Overview

Brief Summary

Chronic Obstructive Pulmonary Disease (COPD) is projected to be the fifth leading burden of disease worldwide by the year 2020. An acute exacerbation of COPD (AECOPD) is defined as an acute event characterized by a worsening of the patient's respiratory symptoms that requires a modification in the medication. AECOPD are frequent (mean of 1-4 exacerbations each year). It increases in frequency with the severity of the disease. The objective of this study is to examine whether a physical therapy intervention can reduce impairment in patients with COPD during hospitalization due to an acute exacerbation.

Detailed Description

Chronic obstructive pulmonary disease (COPD) is one of the leading diseases causing mortality and morbidity, despite advanced pharmacotherapy and therapeutic management. COPD patients suffer frequent exacerbations, defined as 'acute events characterized by a worsening of the patient's respiratory symptoms that is beyond normal day-to-day variations and leads to a change in medication'. Acute illness and prolonged bed rest are associated with loss of muscle mass and a significant decline in functional ability and mobility. Interventions to counteract these impairments are indicated.

Registry
clinicaltrials.gov
Start Date
September 2015
End Date
July 2018
Last Updated
7 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Marie Carmen Valenza

PhD

Universidad de Granada

Eligibility Criteria

Inclusion Criteria

  • COPD diagnosis with exacerbation.
  • No contraindication of physiotherapy.
  • Signed written consent.
  • Medical approval for inclusion

Exclusion Criteria

  • Neurological, orthopedic or heart diseases.
  • Prosthetic devices in the lower limbs.

Arms & Interventions

Physiotherapy program

Patients with COPD are included in this group. They will receive a physiotherapy program during the hospitalization due to acute exacerbation of COPD, additionally to the standard medical treatment

Intervention: Physiotherapy program

Control group

Patients with COPD are included in this group. They will receive the medical standard treatment during the hospitalization due to acute exacerbation of COPD.

Intervention: Medical standard treatment

Outcomes

Primary Outcomes

Muscle strength

Time Frame: Participants will be followed for the duration of hospital stay, an expected average of 9 days.

Quadriceps strength will be assessed with a portable dynamometer. The test will be performed as previously reported

Exercise capacity

Time Frame: Participants will be followed for the duration of hospital stay, an expected average of 9 days.

Five times sit to stand test (5STS) will be used to assess exercise capacity, 5STS is a simple assessment tool that is feasible in all healthcare settings, and may be a rapid method of assessing changes in exercise capacity in COPD and screening for poor physical functioning individuals.

Secondary Outcomes

  • Impact of COPD(Participants will be followed for the duration of hospital stay, an expected average of 9 days.)
  • Respiratory function(Participants will be followed for the duration of hospital stay, an expected average of 9 days.)
  • Fatigue(Participants will be followed for the duration of hospital stay, an expected average of 9 days.)
  • Dyspnea(Participants will be followed for the duration of hospital stay, an expected average of 9 days.)
  • Health status(Participants will be followed for the duration of hospital stay, an expected average of 9 days.)

Study Sites (2)

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