Obesity in Sleep Medicine - Focusing on OHS Phenotypes
Completed
- Conditions
- Obesity Hypoventilation Syndrome (OHS)
- Registration Number
- NCT04570540
- Lead Sponsor
- Wissenschaftliches Institut Bethanien e.V
- Brief Summary
This study focuses on a comprehensive examination of obese patients with sleep-related breathing disorders including patients with OSA, sleep hypoventilation and OHS. The aim of this study is to (1) evaluate characteristics of and differences between severity levels of obesity-related breathing disorders, (2) discuss pathophysiological variables associated with hypoventilation during sleep or at daytime and (3) find functional parameters indicating sleep hypoventilation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 82
Inclusion Criteria
- Age ≥18 years
- BMI ≥ 30 kg/m²
- Indication for sleep lab admission or indication for BiLevel or non-invasive ventilation therapy initiation due to existing hypoventilation/OHS
Exclusion Criteria
- Age <18 years
- Pregnancy, Lactation
- Any medical, psychological or other condition impairing the patient's ability to provide informed consent.
- Missing informed consent
- Participation in another clinical study
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hypercapnic ventilatory response Within 48 hours of sleep lab admission
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Institut für Pneumologie an der Universität zu Köln / Wissenschaftliches Institut Bethanien für Pneumologie e.V.
🇩🇪Solingen, Nordrhein-Westfalen, Germany
Institut für Pneumologie an der Universität zu Köln / Wissenschaftliches Institut Bethanien für Pneumologie e.V.🇩🇪Solingen, Nordrhein-Westfalen, Germany