Placental ULtraSound Evaluation in assisted reproductive technology

Recruiting

• Conditions: subfertiliteit; reduced fertility; Subfertility; 10035129

• Registration Number: NL-OMON48373
• Lead Sponsor: Medisch Universitair Ziekenhuis Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 264

Inclusion Criteria

- Maternal age >= 18 years
- Singleton pregnancy
- Naturally conceived or conceived after IVF or ICSI with or without
pre-implantation genetic testing (PGT)
- Good understanding of the Dutch language
- BMI <= 35 kg/m2

Exclusion Criteria

- Pregnant via other ART-treatments such as ovulation induction (OI),
intra-uterine insemination (IUI) or controlled ovarian hyperstimulation (COH)
only.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary endpoints are morphological placental characteristics such as placental<br /><br>calcifications, placental lakes and placental location, and vascular placental<br /><br>characteristics such as vascularisation index. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoints are placenta biomarkers such as &beta;-hCG, PAPP-A, PlGF and<br /><br>sFlt-1, foetal development, cell-free fetal DNA fraction in maternal plasma in<br /><br>NIPT and neonatal outcomes.</p><br>