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临床试验/NCT02600052
NCT02600052Unknown不适用

Efficacy of Pattern Respiratory Proprioceptive Neuromuscular Facilitation Associated With Aerobic Training on the Volumes, Lung Capacity and Six-minute Walking Test in Individuals With Parkinson: Randomized Clinical Trial

Universidade Federal de Pernambuco2 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2016年5月最近更新:
适应症

试验速览

阶段
不适用
入组人数
30
试验地点
2
主要终点
LUNG VOLUME

研究概览

简要总结

INTRODUCTION:

Parkinson's disease (PD) is a neurodegenerative disorder that causes motor disorders such as bradykinesia, rigidity and tremor. In addition to the motor symptoms occurring in the overall PD patients, mostly there is associated respiratory disorders. The respiratory impairment may be due by postural changes, limiting the flexibility and expandability of the chest wall causing decreased lung volumes and flows. So the exercise Proprioceptive Neuromuscular Facilitation (PNF) is a tool designed to reduce the changes in respiratory function, the commitment of the respiratory muscles, and allows greater flexibility of the chest wall, reducing the rigidity of the rib cage. To evaluate the effects of respiratory pattern of Proprioceptive Neuromuscular Facilitation on the distribution of pulmonary ventilation, compartmental volumes of diaphragmatic mobility and functional capacity in patients with Parkinson's disease.

METHODS:

The study is a clinical trial randomized, in which participants to be elected for the study should present diagnosis of PD, staging of disease between II and III according to Hoehn and Yahr. Initially, the participants will undergo the collection of data on medical history, assessment of pulmonary function by spirometry and respiratory muscle strength measured by the manometer. Then will undergo evaluation of the breathing pattern and tricompartmental distribution of the volume of the chest wall by hemithorax by Plethysmography Optoelectronic; Quantify the mobility of the right diaphragm in total lung capacity for maneuver and during the current volume by ultrasonography. After the evaluation, participants will undergo intervention which will consist of three stages: first occur first session of the PNF later aerobic training for 30 minutes, ending with one PNF session.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Investigator, Outcomes Assessor)

入排标准

年龄范围
40 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Individuals with stage II and III between the Hoehn and Yahr classification;
  • minimum score of 28 on the Mini Mental Examination for Parkinson.

排除标准

  • individuals with rheumatologic or orthopedic diseases or deformities / abnormalities in the spine that compromise the respiratory mechanics;
  • respiratory comorbidities;
  • history of smoking;
  • history of thoracic or abdominal surgery;
  • clinical instability characterized by infections and / or hemodynamic defined as greater than 150 bpm heart rate or systolic blood pressure less than 90 mmHg;
  • Not present exchange of the drug in the last 30 days.

结局指标

主要结局

LUNG VOLUME

时间窗: 1 MONTH

BY OPTOELECTRONIC PLETHYSMOGRAPHY

WALKING DISTANCE, VO2, VCO2

时间窗: 1 MONTH

SIX-MINUTE WALK TEST PLUS CÓRTEX

次要结局

  • DIAPHRAGM MOBILITY(1 MONTH)
  • DIAPHRAGM THICKNESS(1 MONTH)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Carlos Rego Barros

researcher master

Universidade Federal de Pernambuco

研究点 (2)

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