Evaluation of the effect and safety of fractional PDL and CO2 lasers on burn scars

Phase 3

Completed

• Conditions: treatment of hypertrophic or keloidal burn scars.

• Registration Number: IRCT20201005048928N1
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 August 2022

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

All patients with hypertrophic scars caused by burn

Exclusion Criteria

Women who are included in the study should not breastfeed
Women who are included in the study should not be pregnant
Study participants should not have used lasers for the past 1 month.
Study participants should not have used topical or injectable corticosteroids in the past 1 month
?Study participants shouldn't have underlying diseases that interfere with the healing process of the scar; Like diabetes

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Effectiveness of co2 laser fractional + PDL laser vs each one alone in terms of scar improvement. Timepoint: Before starting treatment, 40 days after the last treatment session. Method of measurement: Due to the Total Vancouver Scar Scale, color of the scar, vascular distribution of the scar, flexibility of the scar, height of the scar.;CO2 fractional laser + PDL safety in comparison with each alone in terms of scar improvement. Timepoint: 40 days after the last treatment session. Method of measurement: Prolonged pain or burning, prolonged redness or erythema, post-inflammatory hyperpigmentation (PIH) and even laser site infection.

Secondary Outcome Measures

Name	Time	Method
Patient's satisfaction with the outcome of treatment. Timepoint: 40 days after the last visit. Method of measurement: questionnaire.