Dermabrasion in Mohs: Split-Scar Trial

Not Applicable

Not yet recruiting

• Conditions: Wound Heal

• Registration Number: NCT07213921
• Lead Sponsor: University of Wisconsin, Madison

Brief Summary

The purpose of this study is to determine the potential influence of intraoperative dermabrasion on scars following Mohs Micrographic Surgery (MMS). Researchers are trying to determine if dermabrasion, a method to gently remove the top layer of your skin, is a good or bad tool to improve scar appearance after healing. The use of dermabrasion technique in this study is considered investigational. 50 participants will be enrolled and on study for up to 6 months.

Detailed Description

Primary Objective: Scar assessment at 3 months postoperatively by utilizing observer component of Patient and Observer Scar Assessment Scale (POSAS)

Secondary Objectives:

* Patient portion of POSAS

* Overall patient opinion of scar appearance

* Complication rate

Study Timeline

• Status Verified: 2025-10
• Study Start: 2025-10-01
• Study First Submitted: 2025-10-06
• Study First Submitted QC: 2025-10-06
• Last Update Submitted: 2025-10-06
• Study First Posted: 2025-10-09
• Last Update Posted: 2025-10-09
• Primary Completion: 2026-09
• Study Completion: 2026-09-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Able to give informed consent themselves
• Scheduled for cutaneous surgical procedure on the face or neck with predicted linear closure greater than 4 centimeters.
• Willing to return for follow up visit within the evaluation period

Exclusion Criteria

• Patients with impaired decision-making capacity
• Significant vision or hearing impairments
• Pregnant Individuals
• Incarceration
• Wounds with predicted closure length less than 4 cm

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
POSAS Observer Score at 3 months post-surgery	3 months post-surgery	The investigators hypothesize that the side of the wound treated with intraoperative dermabrasion will have superior cosmesis as evaluated by the observer components of POSAS when evaluated at 3 months postoperatively. Two blinded reviewers will provide the POSAS Observer score which evaluates scar vascularity, pigmentation, thickness, relief, pliability, and surface area, each from 1 to 10 where higher scores indicate worse scars. Total scores are summed and range from 6-60.

Secondary Outcome Measures

Name	Time	Method
POSAS Patient Score at 3 months post-surgery	3 months post-surgery	The investigators hypothesize that the side of the wound treated with intraoperative dermabrasion will have superior cosmesis as evaluated by the patient components of POSAS when evaluated at 3 months postoperatively. The POSAS Patient score evaluates scar pain, itching, color, stiffness, thickness, and irregularity, each from 1 to 10 where higher scores indicate worse symptoms or physical scar characteristics. Total scores are summed and range from 6-60.
POSAS Overall Patient Opinion Score at 3 months post-surgery	3 months post-surgery	The investigators hypothesize that the side of the wound treated with intraoperative dermabrasion will have superior cosmesis as evaluated by the patient components of POSAS when evaluated at 3 months postoperatively. The POSAS overall patient opinion score ranges from 1 to 10 where higher scores indicate worse symptoms or physical scar characteristics.
Number of Complications	3 months post-surgery

Trial Locations

Locations (1)

UW Health Mohs Surgery Clinic; 🇺🇸 Madison, Wisconsin, United States