EUCTR2009-011543-40-GB
Active, not recruiting
Phase 1
Assessment of platelet inhibitory response to clopidogrel when coadministered with a proton pump inhibitor - Plavix and PPI study
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Papworth Hospital
- Enrollment
- 72
- Status
- Active, not recruiting
- Last Updated
- 5 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Able to consent
- •Elective PCI
- •Bleeding risk (eScore\>15\) and indication for PPI when on DAP
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range
- •F.1\.3 Elderly (\>\=65 years) yes
- •F.1\.3\.1 Number of subjects for this age range
Exclusion Criteria
- •Allergic to omeprazole, rabeprazole or ranitidine
- •Already on a PPI
Outcomes
Primary Outcomes
Not specified
Similar Trials
Active, not recruiting
Not Applicable
Assessing Platelet Inhibitory Response to Clopidogrel – Feasibility, Safety and Cost Analysis of a Tailored Platelet Inhibition Strategy for Elective PCI Patients - Plavix and PrasugrelTo investigate the feasibility, safety and cost of using the platelet assay VerifyNow-P2Y12 to guide optimal P2Y12 platelet inhibition in patients undergoing elective PCI, compared with standard treatment, at a UK tertiary referral cardiology centre.EUCTR2010-018435-18-GBPapworth Hospital NHS Foundation Trust200
Completed
Phase 4
Inhibition of platelet activation by clopidogrel in type II diabetes mellitus patientsdiabetes mellitus / diabetes1003553410012653NL-OMON32343niversitair Medisch Centrum Utrecht24
Completed
Phase 4
ASsesment of Platelet function and Inhibition in patients Recovering from severe INfectionAcute myocardial infarctionHeart attack10011082NL-OMON50157Vrije Universiteit Medisch Centrum97
Active, not recruiting
Phase 1
Evaluation of platelet activity in patients recovering from a severe infectioHyperaggregability of thrombocytes triggered by severe infection (i.e. pneumonia or invasive urinary tract infection or a cutaneous infection).Therapeutic area: Diseases [C] - Cardiovascular Diseases [C14]EUCTR2016-004303-32-NLVU university medical center62
Active, not recruiting
Not Applicable
Anti-inflammatory and Anti-platelet effect of Clopidogrel and Aspirin vs Aspirin alone in Symptomatic Polyvascular disease and in patients with multiple recurrent cardiovascular events. - NDPolyvascular disease and in patients with multiple recurrent cardiovascular events.MedDRA version: 9.1Level: LLTClassification code 10032377Term: Other peripheral vascular diseaseMedDRA version: 9.1Level: LLTClassification code 10028600Term: Myocardial ischaemiaEUCTR2008-004626-17-ITPOLICLINICO UNIVERSITARIO AGOSTINO GEMELLI