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Clinical Trials/NCT07411274
NCT07411274
Not yet recruiting
Phase 3

Comparison of Ultrasound-Guided vs. Conventional Scalp Block for Postoperative Analgesia in Pediatric Supratentorial Tumor Surgeries: A Randomized Controlled Trial.

Cairo University0 sites74 target enrollmentStarted: February 1, 2026Last updated:

Overview

Phase
Phase 3
Status
Not yet recruiting
Enrollment
74
Primary Endpoint
Mean arterial blood pressure intraoperatively from baseline till skin incision

Overview

Brief Summary

Although scalp nerve blocks have been shown to provide effective postoperative analgesia in pediatric neurosurgical procedures, limited data exist on their use under ultrasound guidance. The smaller anatomical structures and higher vascularity of the pediatric scalp increase the risk of inadvertent vessel puncture or systemic toxicity with landmark-based techniques. Ultrasound guidance enables direct visualization of the targeted nerves and adjacent vessels, potentially improving block accuracy and safety. To date, no randomized controlled trial has compared ultrasound-guided versus conventional scalp block specifically in pediatric supratentorial tumor surgeries. This study aims to fill this gap.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
Double (Participant, Outcomes Assessor)

Eligibility Criteria

Ages
2 Years to 12 Years (Child)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • American Society of Anesthesiologists (ASA) physical status I, II.
  • Undergoing elective supratentorial tumor surgery under general anesthesia on one side of the head.

Exclusion Criteria

  • Urgent/emergency craniotomy.
  • Coagulopathy or platelet dysfunction.
  • Allergy to local anesthetics.
  • Pre-existing bradycardia (HR \<60 bpm in infants, \<50 bpm in older children) or unstable arrhythmias.
  • Severe hepatic/renal impairment.

Arms & Interventions

Ultrasound-guided scalp block using bupivacaine

Active Comparator

patients will recieve ultrasound-guided scalp block using bupivacaine

Intervention: Ultrasound-guided scalp block (Procedure)

conventional scalp block using bupivacaine

Active Comparator

patients will recieve conventional scalp block with bupivacaine using a landmark-based technique

Intervention: conventional scalp block (Procedure)

Outcomes

Primary Outcomes

Mean arterial blood pressure intraoperatively from baseline till skin incision

Time Frame: from 5 minutes immediately before skin incision till the peak mean arterial blood pressure recorded within the first minute after incision

The mean arterial blood pressure recorded during 5 minutes immediately before skin incision till the peak mean arterial blood pressure recorded within the first minute after incision

Secondary Outcomes

  • Duration of analgesia(24 hours postoperatively)
  • objective pain scale(2, 4, 6, 8, 12, 16, and 24 hours postoperatively)
  • Total doses of ketorolac(24 hours postoperatively)
  • 6. Total dose of paracetamol(24 hours postoperatively)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

AbdElKhalik Mahmoud Shaban

Lecturer of anaesthesia

Cairo University

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