NCT02009891CompletedNot Applicable
The Application of a Validated Patient and Clinic Specific Predictive Model to Reduce the Incidence of Multiple Births Resulting From Fresh In Vitro Fertilization Cycles
Ottawa Fertility Centre1 site in 1 country200 target enrollmentStarted: June 2012Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- Clinical pregnancy rate at 8 -10 weeks gestational age
Study Overview
Brief Summary
To determine in women undergoing IVF who are at high risk of multiple births (>35%), as calculated by the application of a predictive model - IVFsingleTM, if single embryo transfer will lead to both comparable clinical pregnancy rate (CPR) and other secondary outcomes such as live birth rate (LBR) and cumulative live birth rate (cLBR) in comparison to DET while reducing the incidence of multiple births (a secondary outcome measure).
Study Design
- Study Type
- Observational
- Observational Model
- Other
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 38 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Under 38 1st or second IVF attempt
Exclusion Criteria
- •Over 37 years old donor egg third or greater IVF attempt cancellation in previous cycle for poor response successful pregnancy with IVF -
Outcomes
Primary Outcomes
Clinical pregnancy rate at 8 -10 weeks gestational age
Time Frame: 36 months
Secondary Outcomes
- Multiple pregnancy rate(36 months)
Investigators
Dr. Arthur Leader
Consultant
Ottawa Fertility Centre
Study Sites (1)
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