Titration of Buprenorphine and Naloxone Combination in Poppy Husk Users
Phase 4
- Conditions
- Health Condition 1: F112- Opioid dependence
- Registration Number
- CTRI/2021/06/034326
- Lead Sponsor
- ALL INDIA INSTITUTE OF MEDICAL SCIENCES RAIPUR
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Diagnosed as a patient of opioid dependence as per ICD 10 Diagnostic and clinical
Research criteria for dependence (F11)
-Not On opioid substitution therapy for last 2 months
-Only poppy husk User
-Informed consent for participant
Exclusion Criteria
-Patient dependent on any other substance except Nicotine And Caffeine
- Using opioid in any form other than natural (synthetic, semi synthetic, prescribed
medication etc) for 6 months.
- Patient of other organic brain disorder or of mental retardation and any other psychiatric
disorder.
- Patient of any unstable medical illness requiring priority management.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To come up with an appropriate and optimal dose of OST for initiation of treatment <br/ ><br>in patients dependent to natural opioids.Timepoint: Baseline: Titration of dose of OST in 1 week of in-patient admission. <br/ ><br>Follow up of patient on the titrated, on day 15 and day 30 after discharge from hospital
- Secondary Outcome Measures
Name Time Method -to gauge patientsâ?? satisfaction with the current treatment modality. <br/ ><br>Timepoint: Baseline: During in patient admission <br/ ><br>Follow up: On day 15 and day 30 after discharge from hospital;to see the side effect profile of buprenorphine and naloxone combinationTimepoint: Baseline: During in patient admission <br/ ><br>Follow up: On day 15 and day 30 after discharge from hospital