Genetic Polymorphism and Parkinson's Disease in Taiwanese

Completed

• Conditions: Parkinson's Disease

• Registration Number: NCT01996878
• Lead Sponsor: Changhua Christian Hospital

Brief Summary

To observe and analyze the correlation between Single Nucleotide polymorphisms (SNPs) and the incidence of Parkinson's disease in Taiwanese.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-02
• Primary Completion: 2007-02
• Study Completion: 2013-10
• Status Verified: 2013-11
• Study First Submitted: 2013-11-22
• Study First Submitted QC: 2013-11-22
• Last Update Submitted: 2013-11-22
• Study First Posted: 2013-11-27
• Last Update Posted: 2013-11-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 334

Inclusion Criteria

• Clinical diagnosis of Parkinson's disease (case subjects are diagnosed by the presence of at least three of the five following primary signs: rest tremor, bradykinesia, rigidity, impaired postural refluxes, and the presence of a sustained L-dopa response.)
• Healthy volunteers without Parkinson's disease

Exclusion Criteria

• Cases showing atypical features, including multiple system atrophy and progressive supranuclear gaze palsy, or secondary causes of Parkinsonism, such as neuroleptic drugs, infection, tumor, previous cerebrovascular accident and known toxins

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
single nucleotide polymorphisms in certain candidate genes	2 weeks

Trial Locations

Locations (1)

Department of Neurology, Chang-Hua Christian Hospital; 🇨🇳 Chang-Hua, Taiwan