Outcome of Stapes Surgery in Otosclerotic Patients With Tinnitus
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 32
- 主要终点
- decrease tinnitus
研究概览
简要总结
This study will be conducted on patients with otosclerosis attending Assiut University Hospital and undergo stapedectomy operation Evaluation of each patient will conducted preoperatively and 3 month postoperatively Patient will undergo tinnitogram and tinnitus handicap questionnaire before and after the operation to measure improvement in hearing and tinnitus
详细描述
Otosclerosis is an abnormal bone remodeling in the middle ear The normal dense endochondral layer of the bony otic capsule in the labyrinth is replaced by irregularly laid spongy bone leading to the fixation of the stapes.
- Clinical otosclerosis is more prevalent in females than in males, giving rise to the hypothesis that sex hormones may contribute to the development of disease
- The age of onset is variable, although hearing loss typically begins in the third decade, with a range from first decade to the sixth decade.
In most cases, hearing loss is bilateral (70-85%) and is usually asymmetrical, developing initially in one ear before progressing to the other.
Positive family history of otosclerosis has been previously reported in between 30-70% of cases.
The diagnosis is usually made clinically by
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient with otosclerosis undergo stapes surgery in otorhinology department in Assiut university hospital
- •All patient have tinnitus and conductive hearing loss or mixed hearing loss.
排除标准
- •patient with otosclerosis who don't undergo stapes surgery patient have tinnitus due to causes other than otosclerosis.
结局指标
主要结局
decrease tinnitus
时间窗: 3 month
Measuring tinnitus by tinnitogram By pure tone averages untile patients report that specific tone resemble their tinnitus The unit of measure for sound intensity is the decibel (dB)
次要结局
- Changes in pure tone averages(3 month)
研究者
Doaa Araby Mohamed
Resident doctor at Otolaryngology Departement, Principal Investigator
Assiut University