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临床试验/NCT06223321
NCT06223321进行中(未招募)不适用

The Role of Multislice Computed Tomography in Congenital Heart Diseases in Paediatric Age Group.

Sohag University1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2023年1月3日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
100
试验地点
1
主要终点
Multislice Computed Tomography in congenital heart diseases in Paediatric age group

研究概览

简要总结

This study aims to evaluate the added value of cardiac multislice Computed Tomography in assessment of CHD in pediatrics as a non-invasive presurgical planning method

详细描述

All patients will be subjected to the followings:

  • All children gave an informed consent prior performing the research.

  • Every child was submitted to full history taking.

  • Clinical assessment of the patients will be performed in the form of: measuring of vital signs and anthropometric measurements.

  • Renal function tests(ѕerum creatinine and blood urea).

  • Patients will be prepared for CT as following:

  • Calculation of amount of CM and sedations.

  • The patient will be fasting for 4 hours.

  • The peripheral venous line will placed usually in a right upper limb vein, exercise if cosurgical .

  • The patients will be put in a supine position and at the middle of CT gantry.

  • ECG leads will be put on the chest of the patient. Infants below 6 months will be laid with arms at their side or above their head for image acquisition, positioning the arms above their head is advised, while patients above 6 months of age were positioned with their arms above their head when possible.

  • CT examination will be done by

  • 160 MDCT Toshiba Machine or 128 MDCT GE machine or 160 MDCT Philips Machine:

  • We used the following parameters during cardiac CT scanning:

  • Pitch of 1.3, helical thickness of 0.5 mm and coverage of 32 cm.

  • The radiation dose set to 80-100 kvp.

  • Tube current from 10 to 40 mA/kg.

  • The gantry rotation speed at 0.35-.4 sec.

  • ECG gated Retrospective With MA modulation.

  • Wide FOV.

  • A scout will be taken and dual-phase injection conducted using non ionized contrast material. The total contrast volume is 1.5-3 ml/kg.

  • Scanning begins when contrast filled the LV by bolus tracking.

  • All images were transferred to workstation multiplanar reformation (MPR), maximum (MIP) and minimum (MinIP) intensity projections and volume rendering images will be performed for reporting.

  • Reporting in sequential approach

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
1 Day 至 18 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Patients suspected to have congenital heart disease based on clinical findings.
  • Patients known to have congenital heart diseased based on echocardiography (ECHO) with ECHO findings are not sufficient and referred to perform CT for further assessment

排除标准

  • Post-operative Patients of congenital heart disease.
  • Patients who are known to have hyper susceptibility to iodinated Contrast media reaction, impaired renal functions, respiratory failure, fever and severe asthma and patients with arrhythmia.

结局指标

主要结局

Multislice Computed Tomography in congenital heart diseases in Paediatric age group

时间窗: within one week after Computed Tomography done

added value of cardiac multislice Computed Tomography in assessment of CHD in pediatrics as a non-invasive presurgical planning method (detection of other lesion not seen by other imaging modalities )

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mohamed Ahmed Abdelghany Elsherif

ASSISTANT LECTURE AT DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY DEPARTMENT

Sohag University

研究点 (1)

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