NCT00692848已完成不适用
The Impact of Procalcitonin on the Management of Children Aged 1 to 36 Month Presenting With a Fever Without a Source
St. Justine's Hospital2 个研究点 分布在 1 个国家目标入组 384 人开始时间: 2006年11月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 384
- 试验地点
- 2
- 主要终点
- Difference in prescription of antibiotics between the two groups, excluding those treated for a bacterial infection identified by the ED investigations
研究概览
简要总结
Serious bacterial infections are often difficult to detect in children with fever without source. Procalcitonin is a better blood marker of infection than White blood cell count and possibly than C-reactive protein. This could lead to a reduction in antibiotic prescription. Our objective is to evaluate the impact of Procalcitonin result on antibiotic prescription in children 1 to 36 month old with fever without source and our hypothesis is that it will lower the antibiotic prescription rate
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 1 Month 至 36 Months（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children 1-36 months
- •With rectal temperature >38.0 C
- •And no identified source of infection after history and physical examination
排除标准
- •acquired or congenital immunodeficiency
结局指标
主要结局
Difference in prescription of antibiotics between the two groups, excluding those treated for a bacterial infection identified by the ED investigations
次要结局
- Difference in hospitalization rate between the two groups (excluding those hospitalized for an identified infection)
- Procalcitonin sensitivity and specificity
研究者
研究点 (2)
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