Phase I trial of biweekly Carboplatin plus nab-Paclitaxel with concurrent thoracic radiotherapy in patients with locally advanced non-small cell lung cancer - Phase I trial of biweekly CBDCA + nab-PTX +TRT for LA-NSCLC

Aomori Prefectural Central Hospital0 sites18 target enrollmentMay 1, 2013

Overview

No summary available.

Registry

who.int

Start Date

May 1, 2013

End Date

February 12, 2019

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Sponsor

Aomori Prefectural Central Hospital

•1\) Patients with T3N1\. 2\) Superior vena cava syndrome. 3\) Contralateral hilar lymph node metastasis, malignant plueral, pericardial effusion, carcinomatous lymphangiosis. 4\) Active double cancer. 5\) Active infections requiring systemic treatment. 6\) Severe concurrent disease (Pulmonary fibrosis or interstitial pneumonia, renal failure, hepatic failure, cerebrovascular disease, ischemic heart disease requiring treatment, arrhythmia, cardiac infarction within 6 months before enrollment, hemorrhagic peptic ulcer, poorly controlled diabetes). 7\) Grade 2 or higher peripheral neuropathy. 8\) Positive HBs antigen and/or HCV antibody. 9\) History of Severe drug allergies. 10\) Pregnant females, possibly pregnant females, females wishing to become pregnant and nursing mothers. Males that are currently attempting to produce a pregnancy. 11\) Physician concludes that the patient's participation in this trial is inappropriate.