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临床试验/NCT03465475
NCT03465475已完成不适用

Anesthetic Cost Analysis With Desflurane in Automated Gas Control Mode With Maquet Flow-i Anaesthesia Machine

Inonu University1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2018年7月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
60
试验地点
1
主要终点
Amount of used anesthetic gas (desflurane)

研究概览

简要总结

Inhalation agents constitute the major part of anesthetic drug costs (20% - 25%) and a significant portion of the applied inhalation agents are thrown into the atmosphere through the waste gas system without being absorbed by the patient. The amount of waste gas is directly correlated to the fresh gas flow (FGF). Reducing the TGA during general anesthesia reduces the consumption of inhalant agents and contributes to the reduction of greenhouse gas pollution. Risks such as hypoxia, hypercapnia, inadequate depth of anesthesia and potential toxic gas accumulation were associated with low flow anesthesia, but the patient was provided with adequate safety by following pulse oximetry, capnography, FiO2 and anesthetic gas analysis. We aimed to perform anesthetic cost analysis and patient security in automated gas control mode (AGC).

详细描述

After the ethical approvel 60 adult patients scheduled for hepatectomy will be taken to study. Patients will be monitored after they are taken to the operating room (ECG, NIBP, SpO2, Body Temp, BIS, NIRS, PVI, PI, ORI). After the anesthesia induction and tarakeal entubation, first twenty patient will take 300 mL fresh gas flow with AGC mode (group 1), Second twenty patient will take 600 mL fresh gas flow with AGC mode (group 2), third twenty patient will take 600 mL fresh gas flow with manually. Hemodynamic and gas consumption data will be recorded. An operating room will be reserved for this study.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adult patients undergoing hepatectomy with general anesthesia

排除标准

  • Essential data missing
  • Patient participating in other research projects
  • Drug allergy
  • Anesthetic complication story

结局指标

主要结局

Amount of used anesthetic gas (desflurane)

时间窗: Through study completion, an average of 2 month

Amount of used desflurane will be determined in milliliter by anesthesia machine (Maquet Flow i40) for each patient.

次要结局

  • Heart rate(Through study completion, an average of 2 month)
  • Mean arterial pressure(Through study completion, an average of 2 month)
  • Peripheral oxygen saturation(Through study completion, an average of 2 month)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Yusuf Ziya ÇOLAK

Assistant Professor

Inonu University

研究点 (1)

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