Symptom Clusters in Hong Kong Chinese Children With Blood Cancer

Recruiting

• Conditions: Child
• Interventions: Other: Questionnaire

• Registration Number: NCT04888195
• Lead Sponsor: The Hong Kong Polytechnic University

Brief Summary

Pediatric blood cancer is the most common childhood malignancy. Despite its survival has been substantially improved, children still have to pay a high price for numerous distressing symptoms resulted from chemotherapy. Previous studies related to symptom experiences mainly focus on individual symptoms, rather than on multiple symptoms. Understanding these distressing symptoms may help healthcare professionals to develop appropriate and effective interventions with the aims of alleviating symptom severity and thus promoting the child's psychosocial well-being and quality of life.

Detailed Description

A longitudinal study design will be conducted. A sample of 120 patients age 5-17years, diagnosed with blood cancer but not yet receive any chemotherapy and able to communicate with Cantonese and read Chinese will be recruited in the pediatric oncology ward of Hong Kong Children's Hospital.

Study Timeline

• Study First Submitted: 2021-05-03
• Study First Submitted QC: 2021-05-11
• Study First Posted: 2021-05-17
• Study Start: 2021-09-01
• Status Verified: 2022-04
• Last Update Submitted: 2022-04-12
• Last Update Posted: 2022-04-19
• Primary Completion: 2024-09-01
• Study Completion: 2024-09-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• aged 5 - 17 years old
• diagnosed with blood cancer but not yet receive any chemotherapy
• able to communicate with Cantonese and read Chinese

Exclusion Criteria

• who are scheduled to have concurrent cancer treatment
• with recurrent malignancy
• medical condition, or cognitive and learning problems in their medical records

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Questionnaire	Questionnaire	This study aims to examine the cancer patient's symptom clusters and their changes over chemotherapy among pediatric patients with blood cancer in Hong Kong

Primary Outcome Measures

Name	Time	Method
The therapy-related symptom checklist for children (TRSC-C)	Before chemotherapy	For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.
The therapy-related symptom checklist for children (TRSC-C) at 3-month	At 3-month follow-up	For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.
The therapy-related symptom checklist for children (TRSC-C) at 1-week	At 1-week follow-up	For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.
The therapy-related symptom checklist for children (TRSC-C) at 1-month	At 1-month follow-up	For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.
The therapy-related symptom checklist for children (TRSC-C) at 6-month	At 6-month follow-up	For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.
Demographic sheet	At baseline	collect the background information of our subjects, including their age, gender, educational attainment, parents' marital status and religious belief

Trial Locations

Locations (1)

Ka Yan Ho; 🇭🇰 Hong Kong, Hong Kong,China, Hong Kong