An open labelled randomized controlled trial to evaluate the efficacy of dwipanchmooladi tailam matra basti , singhnad guggulu, baluka swedana in the management of aamvata w.s.r. to rheumatoid arthritis
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- The proportion of patients showing improvement in the level of Anti CCP post Basti Karma
研究概览
简要总结
Ama and Vata are two words that makeup Aamvata. Ama is thought to be one of the key
variables that contributes the onset of illness in the body, due to intae of viruddha aahara,
viruddha cheshta, mandagni, avyayaam, snigdha bhukta vyayaam etc. As a result Ama rasa is
formed. This Ama is capable to vitiate the doshas, which then circulates in the form of ama and
settles in Shleshmasthana where kha-vaigunya is present and cause daurbalya, hridyagaurava,
stabdhata etc.Due to their comparable clinical presentations, Aamvata and Rheumatoid Arthritis (R.A) may be
connected. Rheumatoid arthritis is a chronic systemic inflammatory disease, R.A clinically
presents as polyartheritis involving small and large diarthrodial joints of the extremities usually
in asymmetrical pattern.The objectives of treatment for rheumatoid arthritis include reducing pain,
inflammation preventing or delaying further joint damage, preserving function at present and
relieving weakness and fatigue. Acharya Chakradutta explained the chikitsa sutra of aamvata as
Langhan, Swedana, Katu-Tikta, Dipniya Dravya, Virechana, Snehpaan, Anuvasanabasti,
KsharBasti. Dwipanchmoola dravya have properties like Tikta, Kashaya, Madhur rasa, Laghu,
Ushnaguna, Tridoshhara, Aampachana, Sarvajwarhara. In Ayurveda, Basti treatment is the best
amongst panchkarma for Vatvyadhies as it serves manifold purpose. MatraBasti is a type of
SnehaBasti, which is unique therapeutic procedure because of its preventive, promotive,
rejuvenative and curative properties which helps to suppress Vata.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 30.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients willing to sign the consent form Patients between the age group of 30 to 60 years of either sex Both fresh and treated Patients presenting with clinical features of Aamvata mentioned in texts Assessment of Rheumatoid arthritis by assessment criteria ARA criteria and ACR and EULAR criteria Patients with chronicity of disease less than 5 years Patients fit for Basti Karma Anti CCP above normal range and or R A Factor above normal range and or ESR value should not exceeds 80 mg per dl and or CRP value above 1 mg per dl.
排除标准
- •Subjects with chronicity of disease more than 5 years Subjects of either sex age below 30 years and above 60 years The patients unfit for Basti Karma Patients having systemic pathologies like Cardiac disease and Hypertension Uncontrolled Diabetes Endocrine disorders TB of spine Spinal tumours Vertebral fractures Surgical conditions and Auto Immune disease like Ankylosing spondylitis Already diagnosed For both groups Rectal prolapse Fever Pregnant and Lactating mothers Patients with Renal and Hepatic impairment and requiring emergency treatment.
结局指标
主要结局
The proportion of patients showing improvement in the level of Anti CCP post Basti Karma
时间窗: 1st - 0 Day | 2nd - After the completion of trial | 3rd - On follow up
次要结局
- Reduction in R.A Factor level of the patient(Reduction in ESR level of the patient)
研究者
Pooja Rani
Institute for Ayurved Studies and Research