â??Effect of Neuromodulation on Ipseity Encoding in Schizophrenia Patients withPersistent Auditory Hallucinations: Neurocognitive, Neurophysiological & NeuroimagingStudiesâ??

DBT/Wellcome Trust India Alliance (India Alliance)0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年4月3日

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•1. Schizophrenia Diagnosis according to the DSM-5 2. Age 18-45 years;
•3. Any sex;
•4. Right-Handedness using Edinburgh Handedness Inventory
•5. Persistence of auditory hallucinations without remission despite treatment with at least one antipsychotic medication at an adequate dose for a minimum duration of six weeks. (Non-remission is defined as a score of moderate or high ( >2) on the Global Rating of Hallucinations in the scale for the assessment of positive symptoms (SAPS)
•6. Capacity to consent for research studies as per the assessment using the University of California, San Diego Brief Assessment of Capacity to Consent (UBACC)
•7. Ability to provide written informed consent.

•1. Psychiatric emergency necessitating electroconvulsive therapy;
•2. Suicidal risk / any psychiatric emergency;
•3. Score of > 6 on Calgary Depression Rating Scale (Addington et al.,1994);
•4. Pregnancy / Post-Partum;
•5. substance use disorder in last six months (except caffeine ornicotine);
•6. Co-morbid neurological / medical disease that can affect the brain structure / function.
•7. Any Contraindication for Magnetic Resonance Imaging;
•8. Any Contraindication for Transcranial Magnetic Stimulation.
•9. Any Contraindication for Transcranial Direct Current Stimulation. 10. Hearing impairment
•11. History of significant head injury (loss of consciousness more than30 minutes or any permanent sequelae)

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