EFFECT OF USING OZONIZED WATER FOR TEETH CLEANING(DENTAL THERAPY) IN TREATMENT OF GUM DISEASE

Phase 1

Not yet recruiting

• Conditions: Abnormal findings in other body fluids and substances,

• Registration Number: CTRI/2020/07/026275
• Lead Sponsor: NIRANJANA J MOHAN

Brief Summary

Ozone has been shown topossess unique properties and has potential applications to the clinicalpractice of dentistry and medicine. Ozone oxidizes biomolecules, disruptsmicrobial cell structures and metabolism. Ozone disrupts microbial cell walls inseconds, leading to immediate cell lysis. An ozone application of 10 – 20 secondhas been reported to eliminate more than 99% of the microorganisms found in thedental caries .Ozone has been applied for treatment of earlycarious lesions, sterilization of cavities, root canals, enhancing epithelial woundhealing such as ulcerations and herpetic lesions

Periodontitisis a chronic multifactorial inflammatory disease of microbial origin. Thebeneficial properties of ozone such as antimicrobial (bactericidal, viricidal,and fungicidal) immunostimulating, immune modulatory and anti-inflammatorymakes it an excellent choice for treatment of periodontitis

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2020-06-25
• Study Start: 2020-07-15

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patients with Generalized Stage III periodontitis ( diagnosed according to 2017 world workshop on the classification of periodontal and peri-implant diseases and conditions) Patients with minimum of 20 remaining teeth Subjects with Probing Pocket Depth (PPD) greater than or equal to 5mm.
• Subjects with gingival index score greater than or equal to 1.
• Subjects who have not received periodontal therapy within the last 6 months.
• Those willing to participate in the study.

Exclusion Criteria

• Patients with systemic diseases which contraindicate periodontal surgical procedures Patients who have taken antibiotics or anti-inflammatory drugs for the past 3 months Pregnant and lactating females.
• Immunocompromised patients Patients who are undergoing orthodontic treatment.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Results of evaluation of clinical parameters	20 minutes

Secondary Outcome Measures

Name	Time	Method
Results of biochemical analysis of saliva and indices like Plaque Index	(Turesky- Gilmore-Glickman modification of Quigley –Hein), Gingival Index

Trial Locations

Locations (1)

PMS COLLEGE OF DENTAL SCIENCE AND RESEARCH; 🇮🇳 Thiruvananthapuram, KERALA, India

PMS COLLEGE OF DENTAL SCIENCE AND RESEARCH

🇮🇳Thiruvananthapuram, KERALA, India

NIRANJANA J MOHAN

Principal investigator

7907153733

niranjanajmohan@hotmail.com