NCT06094985招募中不适用
Prognostic Markers for a Better Follow-up in Head and Neck Cancer.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Recurrence
研究概览
简要总结
To identify tumor specific DNA mutations and aberrations and to follow these in blood over time to predict treatment response/survival and secondly to correlate presence of these markers in blood to pathological parameters (LVI, Pn, WPOI and margins), radiological findings and to tumor stage.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient diagnosed with head and neck cancer
- •Treatment includes surgery
- •Consent to participate
排除标准
- •No consent
- •Age below 18 years
- •No surgery
- •No tumor material to sample
结局指标
主要结局
Recurrence
时间窗: 2 years
Recurrent disease within 2 years after surgery. Is presence of these DNA changes in blood correlated to recurrence?
Survival
时间窗: 2 years
Alive/dead. Is presence of these DNA changes in blood correlated to survival?
Treatment response
时间窗: 6 months
Is presence of these DNA changes in blood correlated to treatment response?
次要结局
- Radiological parameters(9 months)
- Pathological parameters(6 months)
- Stage(2 years)
研究者
Anders Näsman
Assoc Prof
Karolinska Institutet
研究点 (1)
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