Effect of fecal microbita transplantation in treatment of PCOS

Phase 1

• Conditions: E28.2; Poly-cystic ovary syndrome.; Polycystic ovarian syndrome

• Registration Number: IRCT20190523043674N1
• Lead Sponsor: Boushehr University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 October 2019

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 15

Inclusion Criteria

Adult women 15-35
Currently diagnosed PCOS patient without treatment
PCOS patient with long time treatment
According to Rotterdam criteria patient must have menstural irregularity, hyperandrogenism and PCOS ultrasonography indices and must not have other diseases (at least two criteria)
More than 1 month menstural irregularity
More than 3 months secondary amenorrhea
Hyperandrogenism signs including acnea and hirsutism
Hyperandrogenemia (total testosterone of serum >0/5 ng/mL)
Non-smoker, without any addiction and non-alcohol consumer patients
Obese patient (BMI>20)
Abnormal uterine bleeding

Exclusion Criteria

Any GI disorders
Immuno-compromised patients or usage of immuno-suppressant drugs
Improving of PCO symptoms after treatment with drugs
Food Allergy
Chronic diarrhea
Antibiotic intake 3 days before transplantation
Any history of cancer
Congenital diseases such as adrenal hyperplesia
Cushing's disease
Acromegaly & Gigantism
Type 1& 2 Diabetes

Study & Design

• Study Type: interventional
• Study Design: Not specified