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Effect of Xen Implantation on the Aqueous Humor Proteome

Terminated
Conditions
Primary Open Angle Glaucoma
Registration Number
NCT04141865
Lead Sponsor
Price Vision Group
Brief Summary

The purpose of this study is to determine how the aqueous humor proteome changes after implantation of a Xen microstent for treatment of glaucoma.

Detailed Description

The purpose of this study is to determine how the aqueous humor proteome changes after implantation of a Xen microstent for treatment of glaucoma using liquid chromatography mass spectrometry.

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
3
Inclusion Criteria
  • Male or female of any racial or ethnic origin, 18 years or older
  • Able to provide written informed consent.
  • Scheduled to undergo Xen implantation for open angle glaucoma or already has an aqueous shunt
Exclusion Criteria
  • History of conjunctivitis or any ocular infection within the past 3 weeks.
  • Any active inflammation of the cornea or the anterior chamber (uveitis)

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Aqueous humor proteomeChange from baseline at 6 months

The aqueous humor proteome will be assessed with liquid chromotography/mass spectometry (quantitative LC-MS/MS).

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Price Vision Group

🇺🇸

Indianapolis, Indiana, United States

Price Vision Group
🇺🇸Indianapolis, Indiana, United States

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