Photoplethysmographic Dichrotic Notch Reflexes Systemic Hemodynamics

Recruiting

• Conditions: Vascular Diseases

• Registration Number: NCT04179097
• Lead Sponsor: Hospital Privado de Comunidad de Mar del Plata

Brief Summary

Changes in the vascular tone of anesthetized patients is common and cause hemodynamic problems. The investigators have previously demonstrated that the shape of the pulse oximetry waveform (photoplethysmography) is closely related to the changes observed in systemic vascular resistence. The main change in pulse waveform is based to the dichrotic notch position. The present study was designed to determine if the dichrotic notch position is related to a local or a systemic change in the vascular tone.

Detailed Description

This is a prospective and observational study designed to determine if the changes observed in finger photoplethysmographic waveform of surgical patients is related to a local or a sistemic changes in the vascular tone. The investigators will studied 15 patients undergoing regional brachial plexus anesthesia for upper limb surgeries. Photoplethysmography will be continuously recorded in the thumb of the tested hand (anesthetized hand) and in the thumb of the control, opposite hand. Duplex color and power Doppler will measure flow in the both brachial arteries and in the aorta (supraesternal view). The contour analysis of both, photoplethysmogram and arterial flow velocities will be analyzed, correlated and compared.

Study Timeline

• Study First Submitted: 2019-09-30
• Study Start: 2019-11-05
• Study First Submitted QC: 2019-11-25
• Study First Posted: 2019-11-26
• Status Verified: 2023-05
• Last Update Submitted: 2023-05-22
• Last Update Posted: 2023-05-23
• Primary Completion: 2023-12-01
• Study Completion: 2023-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• Written Inform Consent
• Programmed surgery
• Supine position

Exclusion Criteria

• Emergency surgery
• Peripheral vascular diseases

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Analysis in the position of the dichrotic notch between photoplethysmogram and spectral Doppler waveforms.	4 hours	The position of the dichrotic notch of pulse waveform in photoplethysmogram (time arrival of diastolic wave expressed in seconds) was compared to the one observed in the spectral Doppler waveform (seconds).

Trial Locations

Locations (2)

Cecilia M. Acosta; 🇦🇷 Mar del Plata, Buenos Aires, Argentina

Hospital Privado de Comunidad; 🇦🇷 Mar del Plata, Buenos Aires, Argentina