Cryotherapy Versus Topical Tricholoacetic Acid 90% in Treatment of Common Warts
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Comparison of cryotherapy and Tricholoracetic acid 90% in treatment of common warts
研究概览
简要总结
Objective: To compare the efficacy of cryotherapy using liquid nitrogen (cryoget method) versus trichloroacetic acid 90% (applicator method) in treatment of common warts.
Study Design: Randomized Control Trial. Place And Duration of Study: Department of Dermatology, CMH Abbottabad from Jun 2022 to Nov, 2022.
详细描述
A total of 60 patients were enrolled in this investigation by non-probability consecutive sampling technique. Sample size was calculated using WHO sample size calculator and patients were randomized into two equal groups, A and B, each comprising of 30 patients through lottery method. Patients with common warts such as hard lesions, raised lumps with rough surfaces at the back of their fingers, around nails and palm of their hands between the ages of 18 and 60 were included, whereas those with genital warts, cardiac, hepatic, renal, or hypercholesterolemia were excluded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patient presented with common warts in dermatology opd
排除标准
- •• Patients with warts on toes and tip of fingers
- •genital warts
- •cardiac, hepatic and renal disease
- •hypercholesterolemia
- •hypersensitivity reactions
研究组 & 干预措施
Group A cryotherapy
Cryotherapy Group A had their warts treated once every two weeks for a total of twelve weeks, with liquid nitrogen using cryoget method for 10 to 15 seconds on each lesion (depending on size, until a narrow white rim of around 1 mm developed around it).
干预措施: CRYOTHERAPY (Drug)
Group B Topical TCA 90%
Topical TCA 90 % Warts in Group B were treated with liquid TCA 90% by an applicator every two weeks for a total of twelve weeks. After 20 minutes, patients were instructed to remove the solution by washing their warts with water or regular saline
干预措施: Tricholoracetic acid (Drug)
结局指标
主要结局
Comparison of cryotherapy and Tricholoracetic acid 90% in treatment of common warts
时间窗: 12 weeks
Outcome was determined at the end of third month and the patients were labelled as cured and the efficacy was labelled as "Yes" in cases with absence of all the lesions. After twelve weeks of therapy, individuals with persistent warts were regarded as cases of treatment failure and efficacy was labelled as "No".
次要结局
未报告次要终点
研究者
Dr kiran gul
Principal investigator
Combined Military Hospital Abbottabad