NCT00164008已完成4 期
Comparison Between Pamidronate and Zoledronic Acid for the Treatment of Heart and Lung Transplant Related Osteopaenia and Osteoporosis
Bayside Health0 个研究点目标入组 56 人开始时间: 2002年10月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 56
- 主要终点
- Bone mineral density of lumbar spine at 12 months as measured by DEXA.
研究概览
简要总结
The purpose of this trial is to see whether zoledronic acid is better than pamidronate to treat low bone density in heart and lung transplant patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •reduced bone density as indicated by a bone density T score <-1.in either the lumbar spine or femoral neck
- •have undergone or are on the waiting list for heart or lung transplantation
- •are receiving adequate calcium and vitamin D therapy
- •have provided written informed consent prior to participation in the trial
排除标准
- •untreated hypogonadism, hypothyroidism or hyperthyroidism
- •acute or major organ rejection or intercurrent illness
- •pregnancy or breastfeeding
结局指标
主要结局
Bone mineral density of lumbar spine at 12 months as measured by DEXA.
次要结局
- Bone mineral density of femoral neck at 12 months as measured by DEXA.
研究者
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