Effects of Non-surgical Periodontal Treatment on Hemogram, Lipid and Glycemic Profiles of Patients With an Indication for Surgical Coronary Revascularization
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 主要终点
- Hemocyte
研究概览
简要总结
Objective: The aim of this study was to examine the effects of non-surgical periodontal treatment on the hemogram, glycemic and lipid profiles in cardiopathic patients with an indication for surgical revascularization.
Materials and Methods: Twenty-two patients with chronic periodontitis, over 35 years of age (mean age 59.45 years) randomly assigned into 2 groups were evaluated. Test group (n=11), received periodontal treatment before the surgical procedure, and control group (n=11), did not received periodontal treatment prior to surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 35 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Undergoing cardiovascular treatment;
- •Eight viable teeth in the oral cavity;
- •Four periodontal sites with periodontal probing depths ≥5mm in different teeth.
排除标准
- 未提供
研究组 & 干预措施
Periodontal treatment
The test group received oral hygiene instructions, supragingival and subgingival scaling and root planning using curettes and an ultrasonic appliance.
干预措施: Periodontal treatment (Procedure)
Control
结局指标
主要结局
Hemocyte
时间窗: Baseline and 90 days after initial exam
Hemocyte presented a non-significant reduction in the test group. Mean difference 0.39 m/mcL
Reduction in probing depth in sites with PPD>3mm
时间窗: Baseline and 90 days after the initial exam
Reduction of 11.4% in probing depth in sites with Periodontal Probing Depth\>3mm
Reduction in probing depth in sites with PPD>5mm
时间窗: Baseline and 90 days after the initial exam
Reduction of 6.3% in probing depth in sites with Periodontal Probing Depth\>5mm
Reduction in probing depth in sites with CAL>3mm
时间窗: Baseline and 90 days after the initial exam
Reduction of 4.6% in probing depth in sites with Clinical Attachment Level \>3mm.
Reduction in probing depth in sites with CAL >5mm
时间窗: Baseline and 90 days after the initial exam
Reduction of 3.6% in probing depth in sites with Clinical Attachment Level \>5mm.
Leukocyte count
时间窗: Baseline and 90 days after the initial exam
Non-significant reduction of leukocyte count in the test group. Mean difference of 74.6 m/mcL.
Glucose
时间窗: Baseline and 90 days after the initial exam
Glucose showed a non-significant increase in the test group. Mean difference of 24.2 mg/dL.
Hemoglobin
时间窗: Baseline and 90 days after initial exam
Non-significant reduction in test group. Mean difference of 0.2 g/dL
Total Cholesterol
时间窗: Baseline and 90 days after initial exam
Significant reduction in the test group. Mean reduction of 27.4 mg/dL.
High density lipid
时间窗: Baseline and 90 days after initial exam
Significant reduction in test group. Mean difference of 8.2 mg/dL.
Low density lipid
时间窗: Baseline and 90 days after initial exam
Non-significant reduction in test group. Mean difference of 8.9 mg/dL.
次要结局
未报告次要终点
研究者
Walmir Júnio de Pinho Reis Rodrigues
Researcher
Rio de Janeiro State University