Molecular point-of-care 'test and treat' for influenza (FluPOC)

Not Applicable

• Conditions: Infection; Infections and Infestations

• Registration Number: ISRCTN17197293
• Lead Sponsor: niversity Hospital Southampton NHS Foundation Trust

Brief Summary

2019 protocol in: https://www.ncbi.nlm.nih.gov/pubmed/31852699 (added 20/12/2019) 2021 results in https://pubmed.ncbi.nlm.nih.gov/33285143/ (added 18/05/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-11-13
• Last Update Posted: 7 June 2021
• Study Completion: 2026-05-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 613

Inclusion Criteria

1. Is a patient in the ED* or AMU at University Hospital Southampton NHS Foundation Trust (UHS) or [added 01/05/2019]: Hampshire Hospitals Foundation NHS Trust
2. Aged =18 years old
3. Has acute respiratory illness**
4. Duration of respiratory illness less than 10 days prior to hospitalisation
5. Can be recruited to the study within 16 hours of presentation

*For patients in ED a decision will have already been made that the patient will be admitted.
**An episode of acute respiratory illness is defined as an acute pulmonary illness (including pneumonia, bronchitis and influenza-like illness) or an acute exacerbation of a chronic respiratory illness (including exacerbation of COPD, asthma or bronchiectasis). For the study, acute respiratory illness as a provisional, working, differential or confirmed diagnosis must be made by a treating clinician.

Exclusion Criteria

1. Not fulfilling all the inclusion criteria
2. A purely palliative approach being taken by the treating clinicians
3. Previously included in this study and re-presenting within the last 30 days after hospital discharge
4. Declines nasal / pharyngeal swabbing
5. Consent declined or consultee consent declined
6. Concurrent, prior or subsequent enrolment in an observational study is not necessarily an exclusion criterion; this is at the discretion of the chief investigator and will be assessed on a case-by-case basis.

Study & Design

• Study Type: Interventional
• Study Design: Not specified