Impact of Powdered Tart Cherries on Recovery From Repeated Sprints
- Conditions
- Oxidative StressMuscle DamageInflammationSoreness, Muscle
- Interventions
- Dietary Supplement: PlaceboDietary Supplement: Tart Cherry Extract Powder
- Registration Number
- NCT06122038
- Lead Sponsor
- Lindenwood University
- Brief Summary
The purpose of this study is to evaluate changes in force and power production, soreness, inflammation, and oxidative stress after repeated sprinting activity and powdered tart cherry ingestion in trained males and females.
- Detailed Description
The purpose of this study is to evaluate changes in force and power production, soreness, inflammation, and oxidative stress after repeated sprinting activity and powdered tart cherry ingestion in trained males and females. This study will utilize a randomized, double-blind, placebo group study design. Prior to any data collection, potential participants will be explained the protocol and then review and sign an IRB-approved consent form. Healthy male and female (n=40) participants who report regularly practicing or competing in high-intensity multi-modal resistance based exercise will complete the study protocol.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
- Healthy male and female (n=40) participants between the ages of 18 - 35 years of age will finish the study protocol. An even distribution of males (n=20) and females (n=20) is planned.
- Participating in some form of exercise at least four days per week with at least two days consisting of some form of high-intensity exercise for the past six months.
- Examples include regular gym attendance to complete resistance training, interval exercise, or participation in some form of organized physical activity involving high-speed running or other forms of high-intensity exercise.
- Have a body mass index (BMI) range of 18.0 - 30.0 kg/m2. Males with a body mass index greater than 30.0 kg/m2, but a body fat percentage less than 27.5% fat will be accepted into the study. Females with a body mass index greater than 30.0 kg/m2, but a body fat percentage less than 32.5% fat will be accepted into the study.
- Participant has a positive medical history of heart disease/cardiovascular disease, uncontrolled hypertension (140/90 or greater mmHg), kidney disease (dialysis or renal failure), hepatic impairment or disease, or Type I or Type II diabetes.
- Participant has a positive medical history of unstable thyroid disease, previously diagnosed major affective disorder, psychiatric disorder that required hospitalization in the prior year, immune disorder (i.e., HIV/AIDS), a history of cancer (except localized skin cancer without metastases or in situ cervical cancer within five years prior to screening visit.
- Participant has an abnormality or obstruction of the gastrointestinal tract precluding swallowing (e.g. dysphagia) and digestion (e.g., known intestinal malabsorption, celiac disease, inflammatory bowel disease, chronic pancreatitis, steatorrhea)
- Positive medical history for any neurological condition or neurological disease
- Currently smoke or have quit within the past six months
- Current daily use of aspirin, NSAIDS, naproxen sodium, COX-2 inhibitors, or any other over-the-counter or prescribed medication indicated for pain relief.
- Intake of any dietary supplement known or purported to impact muscle repair and recovery such as antioxidants, curcumin, turmeric, branched-chain amino acids, vitamin D, tart cherry, pomegranate, fish oils, or creatine monohydrate.
- Individuals who indicate they are actively involved in any form of a dietary program in the past 30 days to lose weight
- Participants who are lactating, pregnant or planning to become pregnant
- Have a known sensitivity or allergy to any of the study products
- Any condition or abnormality that, in the opinion of the investigator, would compromise the safety of the participant or the quality of the study data
- History of alcohol or substance abuse in the 12 months prior to screening
- Receipt or use of an investigational product in another research study within 28 days prior to baseline testing
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Placebo Placebo Rice Flour. Dispensed during visit 1. Participants will consume 1 dose per day for 10 days. Tart Cherry Extract Powder Tart Cherry Extract Powder Tart Cherry Extract Powder (NordicCherry, SpecNova, LLC). Dispensed during visit 1. Participants will consume 1 dose per day for 10 days.
- Primary Outcome Measures
Name Time Method Isokinetic knee extension maximal voluntary contraction. 10 days Peak isokinetic knee extension force (N) from a isokinetic knee extension exercise using a Biodex System 3
Counter movement Jump Height 10 days Jump height from counter movement jump
Counter movement jump peak propulsive force (N) 10 days Peak propulsive force (N) from counter movement jump
Counter movement jump relative breaking force (N) 10 days relative breaking force (N/kg) from counter movement jump
Perceived recovery Visual Analog Scale 10 days Perceived recovery Visual Analog Scale ranging from 0 (worst) to 100 (best)
Pain to Pressure threshold 10 days Pain to Pressure threshold from algometry (higher = less sore). Minimum values are 0 N, maximum values are 110 N
Isometric mid-thigh pull maximal voluntary contraction 10 days Isometric maximal voluntary contraction peak force will be measured using an isometric mid-thigh pull assessment. Peak force production will be measured in Newtons.
Perceived soreness Visual Analog Scale 10 days Perceived soreness Visual Analog Scale ranging from 0 (worst) to 100 (best)
Changes in Creatine Kinase concentrations 10 days Changes in Creatine kinase concentrations following damaging exercise
Changes in Creatine Kinase-myocardial band concentrations 10 days Changes in Creatine kinase-myocardial band concentrations following damaging exercise
Sprint time Baseline Fastest and average sprint time during 15 30-meter sprint recorded using digitally timed timing gates
- Secondary Outcome Measures
Name Time Method Changes in Uric Acid Concentrations 10 days Changes in Uric Acid concentrations
Changes in Protein carbonyls concentration 10 days Protein carbonyls concentration changes
Desire to exercise visual analog scale 10 days Desire to exercise visual analog scale (0 = not ready to train, 100 = very ready to train)
Pittsburgh sleepiness Scale Score 10 days Pittsburgh sleepiness Scale Score (lower scores indicate higher level of sleepiness)
Changes in IL-6 concentration 10 days Changes in IL-6 concentration
Peak power 10 days Peak power during a wingate anaerobic test
Changes in testosterone-cortisol ratio 10 days Testosterone-cortisol ratio changes
Changes in IL-10 concentration 10 days Changes in IL-10 concentration
Changes in 8-isoprostane concentration 10 days 8-isoprostane concentration changes
Changes in TNF-alpha concentration 10 days Changes in TNF-alpha concentration
Trial Locations
- Locations (1)
Exercise and Performance Nutrition Laboratory
🇺🇸Saint Charles, Missouri, United States