Impact of Powdered Tart Cherries on Recovery From Repeated Sprints in Trained Males and Females
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Counter movement Jump Height
研究概览
简要总结
The purpose of this study is to evaluate changes in force and power production, soreness, inflammation, and oxidative stress after repeated sprinting activity and powdered tart cherry ingestion in trained males and females.
详细描述
The purpose of this study is to evaluate changes in force and power production, soreness, inflammation, and oxidative stress after repeated sprinting activity and powdered tart cherry ingestion in trained males and females. This study will utilize a randomized, double-blind, placebo group study design. Prior to any data collection, potential participants will be explained the protocol and then review and sign an IRB-approved consent form. Healthy male and female (n=40) participants who report regularly practicing or competing in high-intensity multi-modal resistance based exercise will complete the study protocol.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
盲法说明
In a double-blind, placebo-controlled fashion, participants will be randomly assigned to one of two supplementation groups. One group will be assigned to ingest rice flour which will serve as a placebo group. The other group will be assigned to ingest 500 mg/day of Tart Cherry Extract Powder (ADSO Naturals). All study materials will be prepared into gelatin capsules of identical size, color, shape, and transparency.
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy male and female (n=40) participants between the ages of 18 - 35 years of age will finish the study protocol. An even distribution of males (n=20) and females (n=20) is planned.
- •Participating in some form of exercise at least four days per week with at least two days consisting of some form of high-intensity exercise for the past six months.
- •Examples include regular gym attendance to complete resistance training, interval exercise, or participation in some form of organized physical activity involving high-speed running or other forms of high-intensity exercise.
- •Have a body mass index (BMI) range of 18.0 - 30.0 kg/m
- •Males with a body mass index greater than 30.0 kg/m2, but a body fat percentage less than 27.5% fat will be accepted into the study. Females with a body mass index greater than 30.0 kg/m2, but a body fat percentage less than 32.5% fat will be accepted into the study.
排除标准
- •Participant has a positive medical history of heart disease/cardiovascular disease, uncontrolled hypertension (140/90 or greater mmHg), kidney disease (dialysis or renal failure), hepatic impairment or disease, or Type I or Type II diabetes.
- •Participant has a positive medical history of unstable thyroid disease, previously diagnosed major affective disorder, psychiatric disorder that required hospitalization in the prior year, immune disorder (i.e., HIV/AIDS), a history of cancer (except localized skin cancer without metastases or in situ cervical cancer within five years prior to screening visit.
- •Participant has an abnormality or obstruction of the gastrointestinal tract precluding swallowing (e.g. dysphagia) and digestion (e.g., known intestinal malabsorption, celiac disease, inflammatory bowel disease, chronic pancreatitis, steatorrhea)
- •Positive medical history for any neurological condition or neurological disease
- •Currently smoke or have quit within the past six months
- •Current daily use of aspirin, NSAIDS, naproxen sodium, COX-2 inhibitors, or any other over-the-counter or prescribed medication indicated for pain relief.
- •Intake of any dietary supplement known or purported to impact muscle repair and recovery such as antioxidants, curcumin, turmeric, branched-chain amino acids, vitamin D, tart cherry, pomegranate, fish oils, or creatine monohydrate.
- •Individuals who indicate they are actively involved in any form of a dietary program in the past 30 days to lose weight
- •Participants who are lactating, pregnant or planning to become pregnant
- •Have a known sensitivity or allergy to any of the study products
- •Any condition or abnormality that, in the opinion of the investigator, would compromise the safety of the participant or the quality of the study data
- •History of alcohol or substance abuse in the 12 months prior to screening
- •Receipt or use of an investigational product in another research study within 28 days prior to baseline testing
结局指标
主要结局
Counter movement Jump Height
时间窗: 10 days
Jump height from counter movement jump
Counter movement jump peak propulsive force (N)
时间窗: 10 days
Peak propulsive force (N) from counter movement jump
Counter movement jump relative breaking force (N)
时间窗: 10 days
relative breaking force (N/kg) from counter movement jump
Perceived recovery Visual Analog Scale
时间窗: 10 days
Perceived recovery Visual Analog Scale ranging from 0 (worst) to 100 (best)
Pain to Pressure threshold
时间窗: 10 days
Pain to Pressure threshold from algometry (higher = less sore). Minimum values are 0 N, maximum values are 110 N
Isokinetic knee extension maximal voluntary contraction.
时间窗: 10 days
Peak isokinetic knee extension force (N) from a isokinetic knee extension exercise using a Biodex System 3
Isometric mid-thigh pull maximal voluntary contraction
时间窗: 10 days
Isometric maximal voluntary contraction peak force will be measured using an isometric mid-thigh pull assessment. Peak force production will be measured in Newtons.
Perceived soreness Visual Analog Scale
时间窗: 10 days
Perceived soreness Visual Analog Scale ranging from 0 (worst) to 100 (best)
Changes in Creatine Kinase concentrations
时间窗: 10 days
Changes in Creatine kinase concentrations following damaging exercise
Changes in Creatine Kinase-myocardial band concentrations
时间窗: 10 days
Changes in Creatine kinase-myocardial band concentrations following damaging exercise
Sprint time
时间窗: Baseline
Fastest and average sprint time during 15 30-meter sprint recorded using digitally timed timing gates
次要结局
- Changes in Protein carbonyls concentration(10 days)
- Desire to exercise visual analog scale(10 days)
- Pittsburgh sleepiness Scale Score(10 days)
- Changes in IL-6 concentration(10 days)
- Peak power(10 days)
- Changes in testosterone-cortisol ratio(10 days)
- Changes in IL-10 concentration(10 days)
- Changes in Uric Acid Concentrations(10 days)
- Changes in 8-isoprostane concentration(10 days)
- Changes in TNF-alpha concentration(10 days)