NCT04682236UnknownNot Applicable
Study of the Evolution Profile of the Renal Doppler in the Perioperative Hepathic Transplantation - Interest in Predicting the Occurence of Acute Postoperative Renal Faillure
University Hospital, Strasbourg, France1 site in 1 country30 target enrollmentStarted: November 25, 2020Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Retrospective analysis of the development profiles of renal dopplers in perioperative liver transplantation
Study Overview
Brief Summary
Liver transplantation is associated with a modification of the perfusion pressures of the abdominal organs (preoperative portal hypertension in connection with liver pathology, and normalization of the perfusion pressures during surgery). This abrupt change in the infusion regime is probably responsible for an alteration in renal function in some patients, and the identification of renal vascular profiles using Doppler could point to pathological profiles, which should be diagnosed early.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patient of full age (≥18 years)
- •Patient operated on at the HUS for a liver transplant, between July 1, 2019 and June 30,
- •Patients having undergone an evaluation of hepatic and renal vascular profiles perioperatively.
- •Patients hospitalized in the surgical intensive care unit after hepatic transplant surgery.
- •Patient not having expressed, after information, the reuse of his data for the purposes of this research
Exclusion Criteria
- •Patient who expressed his opposition to participating in the study
- •Patient with suspected obstructive acute renal failure
- •Stenosis of renal arteries known at the time
- •End-stage renal disease on dialysis
- •Impossibility of giving the subject informed information (difficulties in understanding the subject, etc.)
- •Subject under safeguard of justice
Outcomes
Primary Outcomes
Retrospective analysis of the development profiles of renal dopplers in perioperative liver transplantation
Time Frame: Files analysed retrospectily from July 1st, 2019 to June 30, 2020 will be examined
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
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