Anti enuretic efficacy of Amrabeeja tablet and non pharmacological interventio
- Conditions
- Health Condition 1: N399- Disorder of urinary system, unspecified
- Registration Number
- CTRI/2024/04/065045
- Lead Sponsor
- All India Institute Of Ayurveda
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. Patients between 5 to 10 years of age of either sex.
2. Patient with the complaint of repeated involuntary voiding of urine into bed or clothes at night.
(According to DSM-V Criteria)
3. Parents of patients willing to give assent/consent for the trial.
1. Children with congenital anomalies, chronic ailments like tuberculosis, malignancy, cardiac, and renal disorders.
2. Children suffering from urinary tract infections, diabetes mellitus, worm infestation.
3. Children with the symptomatology of any syndrome.
4. Children with physical disabilities, structural abnormality of the genitourinary system.
5. Parents of the patient not willing to participate in the trial.
6. Any condition which the investigating team considers may jeopardize the participant’s health
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method PART 1- 1. Phytoconstituent analysis of the Amrabeeja tablet. <br/ ><br>2. To search the docking and dynamics based predictive correlation of selected phytoconstituents of <br/ ><br>Amrabeeja with known targets of antidiuretic (Desmopressin). <br/ ><br>PART 2- <br/ ><br>Comparative analysis of Amrabeeja and Desmopressin on V2 receptor activity in Nocturnal <br/ ><br>Enuresis using cell line study. <br/ ><br>PART 3- <br/ ><br>Reduction in Dysfunctional Voiding and Incontinence Symptoms Score (DVISS) in children with <br/ ><br>Shayyamutra (Nocturnal Enuresis) in 2 months.Timepoint: Baseline <br/ ><br>After 2 months of intervention <br/ ><br>After 2 months of follow up
- Secondary Outcome Measures
Name Time Method ilTimepoint: Nil