Block characteristics and hemodynamics changes in one minute delay before transitioning patient to supine, comparison of three different local anaesthetics in spinal anaesthesia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 153
- 试验地点
- 1
- 主要终点
- Sensory and Motor block characteristics in terms of onset, maximum level acheived and duration of block following administration of 0.5% Bupivacaine or 0.5% Levobupivacaine or 0.75% Ropivacaine intrathecally
研究概览
简要总结
Spinal anaesthesia is commonly used for lower limb and lower abdominal surgeries, but immediate supine positioning may cause higher block spread and hemodynamic instability. This study compares 0.5% hyperbaric bupivacaine, 0.5% hyperbaric levobupivacaine, 0.75% hyperbaric ropivacaine when patients are kept sitting for one minute before lying supine. The primary outcomes are sensory and motor block characteristics and secondary outcomes include hemodynamic changes and complications.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients who come under ASA 1 and ASA 2 Patients with height between 150-180cm Patients undergoing infraumbilical surgeries under subarachnoid block.
排除标准
- •Patients who refuse to participate in trail Patient who cannot comprehend, uncooperative patient Pregnant patients Patients who cannot sit Patients with any neurological deficits.
结局指标
主要结局
Sensory and Motor block characteristics in terms of onset, maximum level acheived and duration of block following administration of 0.5% Bupivacaine or 0.5% Levobupivacaine or 0.75% Ropivacaine intrathecally
时间窗: Sensory and Motor block level at baseline , 1 minute, 2 minutes,3 minutes, 4 minutes, 5 minutes, 6 minutes,7 minutes, 8 minutes , 9 minutes, 10 minutes,12 minutes,14 minutes,16 minutes,18 minutes, 20 minutes after intrathecal administration of drug
次要结局
- Hemodynamics changes such as changes in heart rate, blood pressure, blood oxygen saturation & complications such as requiring supplemental dose of analgesia, nausea & vomiting, inadequate spinal anaesthesia requiring either repeating intrathecal drug or converting to general anaesthesia(At time of drug given, 2 minutes,4 minutes,6 minutes,8 minutes, 10 minutes, 12 minutes,14 minutes, 16 minutes, 18 minutes, 20 minutes, 25 minutes,30 minutes,35 minutes, 40 minutes, 45 minutes,50 minutes,55 minutes,60 minutes after drug is given intrathecally)
研究者
Pachigolla Sri Sahiti
KS Hegde Medical Academy